Relics

Slay the Spire 2 has relics in seven rarities (Starter, Common, Uncommon, Rare, Shop, Event and Ancient), and OP.GG counts 298 in the game data of the v0.111.0 public beta. Each character starts with one starter relic that Orobas can upgrade to an Ancient version, and Ancient relics from Neow and the other Ancients replace the first game's boss relics.

0:17 Slay the Spire 2 has relics in seven rarities, Starter, Common, Uncommon, Rare, Shop, Event and Ancient, and OP.GG's relic list counts 298 of them in the game data of the v0.111.0 public beta (Aug 14, 2026). A relic is a permanent item that changes the rules for the rest of the run: each character starts with one, Elites and treasure chests drop more, the Merchant sells them, events give them, and the Ancients, starting with Neow, offer the most powerful ones as blessings in place of the first game's boss relics. This page lists the relics by rarity with their effects. The game is in Early Access and Mega Crit keeps tuning relics, so where a public-beta patch changed an effect after the main branch's v0.107.1 (Jun 19, 2026), the table gives the main-branch effect and labels the beta change.

Quick facts

Rarities	Starter, Common, Uncommon, Rare, Shop, Event, Ancient
Count	298 in OP.GG's list (beta v0.111.0 game data); "over 250" at launch, per Destructoid
Starter relics	Burning Blood, Ring of the Snake, Divine Right, Bound Phylactery, Cracked Core
Ancient upgrade	Touch of Orobas turns your starter relic into its Ancient version
Character relics	Appear only for their character
Where from	Elites, treasure chests, the Merchant, events, Neow and the Ancients
Shop prices	All shop relics 25 Gold cheaper since v0.100.0
Status	Early Access; effects change between patches

Sources: OP.GG: Complete Relic List (beta v0.111.0); Destructoid: All relics; Mega Crit: Major Update #1; Kotaku: Tips And Tricks.

How rarity works

Rarity in Slay the Spire 2 measures complexity more than power. Mega Crit's designer Anthony Giovannetti wrote in the v0.101.0 notes (Mar 27, 2026) that Common relics "are not necessarily weaker, but that they are often simple effects that could add value to most decks. As rarity increases we allow higher complexity and more impact on drafting/play decisions." The same patch moved several relics between rarities to fit that rule.

Character relics, marked with a character below, only show up in that character's runs, per Kotaku (Mar 18, 2026). Some are unlocks: killing 15 bosses with a character opens an Epoch with a relic such as the Silent's Twisted Funnel, the Regent's Mini Regent or the Defect's Gold-Plated Cables. Other Epochs add shared relics, such as "Ancients" (Book of Five Rings, Kusarigama, Ice Cream) and "Scribbles" (Reptile Trinket, Unsettling Lamp, Intimidating Helmet), per Destructoid's Epoch guide (Mar 7, 2026). See Unlocks and the Timeline.

The effect text in every table is OP.GG's, read from the v0.111.0 beta's game data on Oct 26, 2026, shortened where marked.

Starter relics and their Ancient versions

39:40 Every character starts with one relic, and the Act 2 Ancient Orobas can upgrade it: his blessing Touch of Orobas "replace[s] your starter Relic with an Ancient version". The Regent's and Necrobinder's starters are Divine Right and Bound Phylactery in the game; some early previews used other names.

Character	Starter relic	Effect	Ancient version	Effect
Ironclad	Burning Blood	At the end of combat, heal 6 HP	Black Blood	Heal 12 HP at the end of combat
Silent	Ring of the Snake	At the start of each combat, draw 2 additional cards	Ring of the Drake	Draw 2 additional cards at the start of your first 3 turns
Regent	Divine Right	At the start of each combat, gain 3 Stars	Divine Destiny	Gain 6 Stars at the start of each combat; 7 on the public beta since v0.108.0
Necrobinder	Bound Phylactery	At the start of your turn, Summon 1	Phylactery Unbound	Summon 5 at the start of each combat and Summon 2 at the start of your turn
Defect	Cracked Core	At the start of each combat, Channel 1 Lightning	Infused Core	Channel 3 Lightning; Lightning deals 1 additional damage

Source: OP.GG relic list and Orobas event page (game data, beta v0.111.0), read Oct 26, 2026; Divine Destiny's change from Mega Crit's v0.108.0 notes (Jul 3, 2026); Infused Core's extra damage from v0.105.0 (May 8, 2026), on the main branch since Jun 19.

Common relics

Relic	Character	Effect
Amethyst Aubergine		Enemies drop 15 additional Gold
Anchor		Start each combat with 10 Block
Bag of Marbles		At the start of each combat, apply 1 Vulnerable to ALL enemies
Bag of Preparation		At the start of each combat, draw 2 additional cards
Blood Vial		At the start of each combat, heal 2 HP
Bone Flute	Necrobinder	Whenever Osty attacks, gain 2 Block
Book of Five Rings		Every 5 cards you add to your Deck, heal 20 HP
Bronze Scales		Start each combat with 3 Thorns
Centennial Puzzle		The first time you lose HP each combat, draw 3 cards
Data Disk	Defect	Start each combat with 1 Focus
Fencing Manual	Regent	At the start of each combat, Forge 10
Festive Popper		At the start of each combat, deal 9 damage to ALL enemies
Gorget		At the start of each combat, gain 4 Plating
Happy Flower		Every 3 turns, gain 1 Energy
Juzu Bracelet		Regular enemy combats are no longer encountered in ? rooms
Lantern		Start each combat with an additional 1 Energy
Meal Ticket		Whenever you enter a shop room, heal 15 HP
Oddly Smooth Stone		Start each combat with 1 Dexterity
Pendulum		Every 3 turns, draw 1 card
Potion Belt		Upon pickup, gain 2 potion slots
Red Mask		At the start of each combat, apply 1 Weak to ALL enemies
Red Skull	Ironclad	While your HP is at or below 50%, you have 3 additional Strength
Regal Pillow		Whenever you Rest, heal an additional 15 HP
Snecko Skull	Silent	Whenever you apply Poison, apply an additional 1 Poison
Strawberry		Upon pickup, raise your Max HP by 7
Strike Dummy		Cards containing "Strike" deal 3 additional damage
Vajra		Start each combat with 1 Strength
Venerable Tea Set		Whenever you enter a Rest Site, start the next combat with an additional 2 Energy
War Paint		Upon pickup, Upgrade 2 random Skills
Whetstone		Upon pickup, Upgrade 2 random Attacks

Source: OP.GG relic list (game data, beta v0.111.0), read Oct 26, 2026.

Uncommon relics

Relic	Character	Effect
Akabeko		At the start of each combat, gain 8 Vigor
Book Repair Knife	Necrobinder	Whenever a non-Minion enemy dies to Doom, heal 3 HP
Bowler Hat		Gain 25% additional Gold
Candelabra		At the start of your 2nd turn, gain 2 Energy
Eternal Feather		For every 5 cards in your Deck, heal 3 HP whenever you enter a Rest Site
Funerary Mask	Necrobinder	At the start of each combat, add 3 Souls into your Draw Pile
Galactic Dust	Regent	For every 10 Stars spent, gain 10 Block
Gold-Plated Cables	Defect	Your rightmost Orb triggers its passive an additional time
Gremlin Horn		Whenever an enemy dies, gain 1 Energy and draw 1 card
Horn Cleat		At the start of your 2nd turn, gain 14 Block
Joss Paper		Every 5 times you Exhaust a card, draw 1 card
Kusarigama		Every time you play 3 Attacks in a single turn, deal 6 damage to a random enemy
Lasting Candy		Every other combat, your card rewards gain an additional Power
Letter Opener		Every time you play 3 Skills in a single turn, deal 5 damage to ALL enemies
Lucky Fysh		Whenever you add a card to your Deck, gain 15 Gold
Mercury Hourglass		At the start of your turn, deal 3 damage to ALL enemies
Miniature Cannon		Upgraded Attacks deal 3 additional damage
Nunchaku		Every time you play 10 Attacks, gain 1 Energy
Orichalcum		If you end your turn without Block, gain 6 Block
Ornamental Fan		Every time you play 3 Attacks in a single turn, gain 4 Block
Pantograph		At the start of each Boss combat, heal 25 HP
Paper Phrog	Ironclad	Enemies with Vulnerable take 75% more damage rather than 50%
Parrying Shield		If you end a turn with at least 10 Block, deal 6 damage to a random enemy
Pear		Upon pickup, raise your Max HP by 10
Pen Nib		Every 10th Attack you play deals double damage
Permafrost		The first time you play a Power each combat, gain 7 Block
Petrified Toad		At the start of each combat, procure a Potion-Shaped Rock (a 15 damage token potion)
Planisphere		Whenever you enter a ? room, heal 5 HP
Regalite	Regent	Main branch: gain 2 Block whenever you create a card. Public beta: 6 Block the first time each turn (v0.110.0), then 4 (v0.111.0)
Reptile Trinket		Whenever you use a potion, gain 3 Strength this turn
Ripple Basin		If you did not play any Attacks during your turn, gain 4 Block
Self-Forming Clay	Ironclad	Whenever you lose HP in combat, gain 3 Block next turn
Sparkling Rouge		At the start of your 3rd turn, gain 1 Strength and 1 Dexterity
Stone Cracker		At the start of each combat, Upgrade 2 random cards in your Draw Pile for the rest of combat
Symbiotic Virus	Defect	At the start of each combat, Channel 1 Dark
Tingsha	Silent	Whenever you discard a card during your turn, deal 3 damage to a random enemy for each card discarded
Tiny Mailbox		Whenever you Rest, procure 2 random Potions
Tuning Fork		Every time you play 10 Skills, gain 7 Block
Twisted Funnel	Silent	At the start of each combat, apply 4 Poison to ALL enemies
Vambrace		The first time you gain Block from a card each combat, double the amount gained

Source: OP.GG relic list (game data, beta v0.111.0), read Oct 26, 2026; Bowler Hat from Mega Crit's v0.100.0 notes; Regalite's history from v0.103.0, v0.110.0 and v0.111.0.

Rare relics

Relic	Character	Effect
Art of War		If you do not play any Attacks during your turn, gain an additional 1 Energy next turn
Beating Remnant		You cannot lose more than 20 HP in a single turn
Bellows		The first Hand you draw each combat is Upgraded
Big Hat	Necrobinder	At the start of each combat, add 2 random Ethereal cards into your Hand
Bookmark	Necrobinder	At the end of each turn, lower the cost of a random Retained card by 1 until played
Captain's Wheel		At the start of your 3rd turn, gain 18 Block
Chandelier		At the start of your 3rd turn, gain 3 Energy
Charon's Ashes	Ironclad	Whenever you Exhaust a card, deal 3 damage to ALL enemies
Cloak Clasp		At the end of your turn, gain 1 Block for each card in your Hand
Demon Tongue	Ironclad	The first time you lose HP on your turn, heal HP equal to the amount lost
Emotion Chip	Defect	If you lost HP during the previous turn, trigger the passive ability of all Orbs at the start of your turn
Frozen Egg		Whenever you add a Power to your Deck, Upgrade it
Gambling Chip		At the start of each combat, discard any number of cards then draw that many
Game Piece		Whenever you play a Power, draw 1 card
Girya		You can now gain Strength at Rest Sites (3 times max)
Helical Dart	Silent	Whenever you play a Shiv, gain 1 Dexterity this turn
Ice Cream		Energy is now conserved between turns
Intimidating Helmet		Whenever you play a card that costs 2 Energy or more, gain 4 Block
Ivory Tile	Necrobinder	Whenever you play a card that costs 3 Energy or more, gain 1 Energy (threshold per Destructoid)
Kunai		Every time you play 3 Attacks in a single turn, gain 1 Dexterity
Lizard Tail		When your HP would be reduced to 0, heal to 50% of your Max HP instead (works once)
Lunar Pastry	Regent	At the end of your turn, gain 1 Star
Mango		Upon pickup, raise your Max HP by 14
Meat on the Bone		If your HP is at or below 50% at the end of combat, heal 12 HP
Metronome	Defect	The first time you Channel 7 Orbs each combat, deal 30 damage to ALL enemies
Mini Regent	Regent	The first time you spend Stars each turn, gain 1 Strength
Molten Egg		Whenever you add an Attack to your Deck, Upgrade it
Mummified Hand		Whenever you play a Power, a random card in your Hand is free to play that turn
Old Coin		Upon pickup, gain 300 Gold
Orange Dough	Regent	At the start of each combat, add 2 random Colorless cards into your Hand
Paper Krane	Silent	Enemies with Weak deal 40% less damage to you rather than 25%
Pocketwatch		Whenever you play 3 or fewer cards during your turn, draw 3 additional cards at the start of your next turn
Power Cell	Defect	At the start of each combat, add 2 zero-cost cards from your Draw Pile into your Hand
Prayer Wheel		Normal enemies drop an additional card reward
Rainbow Ring		The first time you play an Attack, Skill, and Power each turn, gain 1 Strength and 1 Dexterity
Razor Tooth		Every time you play an Attack or Skill, Upgrade it for the remainder of combat
Ruined Helmet	Ironclad	The first time you gain Strength each combat, double the amount gained
Shovel		You can now dig at Rest Sites to obtain a random Relic
Shuriken		Every time you play 3 Attacks in a single turn, gain 1 Strength
Stone Calendar		At the end of turn 7, deal 52 damage to ALL enemies
Sturdy Clamp		Up to 10 Block persists across turns
The Courier		The merchant no longer runs out of cards, relics, or potions and his prices are reduced by 20%
Tough Bandages	Silent	Whenever you discard a card during your turn, gain 3 Block
Toxic Egg		Whenever you add a Skill to your Deck, Upgrade it
Tungsten Rod		Whenever you would lose HP, lose 1 less
Unceasing Top		Whenever you have no cards in Hand during your turn, draw a card
Unsettling Lamp		Each combat, the first time you play a card that Debuffs an enemy, double its effect
Vexing Puzzlebox		At the start of each combat, add a random card into your Hand; it's free to play this turn
White Beast Statue		Potions always appear in combat rewards
White Star		Elites drop an additional Rare card reward

Source: OP.GG relic list (game data, beta v0.111.0), read Oct 26, 2026; Ivory Tile's threshold from Destructoid (Mar 8, 2026).

Shop relics

Shop relics are sold only by the Merchant (see Merchant and Rest Sites). Since v0.100.0 (Mar 20, 2026 beta, main Apr 17) every shop relic costs 25 Gold less and relics that generate Gold no longer appear in the shop. The effects below are OP.GG's, shortened.

Relic	Character	Effect
Belt Buckle		2 Dexterity while you have no Potions
Bread		Lose Energy on your first turn, gain Energy on all others
Brimstone	Ironclad	+2 Strength each turn, and ALL enemies gain 1 Strength
Burning Sticks		The first Skill you Exhaust each combat returns a copy to your Hand
Cauldron		Brews 5 random Potions
Chemical X		X-cost cards get +2 to X
Dingy Rug		Card rewards can contain Colorless cards
Dolly's Mirror		Copy a card in your Deck
Dragon Fruit		+1 Max HP whenever you gain Gold
Ghost Seed		Strikes and Defends gain Ethereal
Gnarled Hammer		Enchant up to 3 Attacks with Sharp 3
Kifuda		Enchant up to 3 cards with Adroit
Lava Lamp		Upgrade all card rewards if you took no damage
Lee's Waffle		+7 Max HP and heal to full
Membership Card		50% discount on all products
Miniature Tent		Choose any number of options at Rest Sites
Mystic Lighter		Enchanted Attacks deal 9 additional damage
Ninja Scroll	Silent	3 Shivs at the start of each combat
Orrery		Gain 5 card rewards
Punch Dagger		Enchant an Attack with Momentum 5
Ringing Triangle		Retain your Hand on the first turn
Royal Stamp		Enchant an Attack or Skill with Royally Approved
Runic Capacitor	Defect	3 additional Orb Slots
Screaming Flagon		20 damage to ALL enemies if you end your turn with an empty Hand
Sling of Courage		2 Strength in Elite combats
The Abacus		6 Block whenever you shuffle your Draw Pile
Toolbox		Choose 1 of 3 Colorless cards at the start of each combat
Undying Sigil	Necrobinder	Enemies with at least as much Doom as HP deal 50% less damage
Vitruvian Minion	Regent	"Minion" cards deal double damage and gain double Block
Wing Charm		A random card in each card reward gets Swift 1

Source: OP.GG relic list (game data, beta v0.111.0), read Oct 26, 2026; Destructoid for Screaming Flagon and Sling of Courage.

Event relics

21:52 Event relics come from ? room events (see Events), several of them from a single event each, such as the dolls of the Doll Room or the forgotten relics of the Trash Heap.

Relic	Effect	Event
Big Mushroom	+20 Max HP, draw 2 fewer cards each combat	Hungry for Mushrooms
Bing Bong	Add an extra copy of every card added	Doll Room
Bone Tea	Upgrade your starting hand next combat	Tea Master (50 Gold)
Byrdpip	Gain Byrd Swoop; a Byrdpip accompanies you in battles	Byrdonis Nest (Byrd Swoop comes from hatching its egg)
Darkstone Periapt	+6 Max HP per Curse	Trash Heap
Daughter of the Wind	1 Block per Attack played	Doll Room
Dream Catcher	Add a card when you Rest	Trash Heap
Ember Tea	2 Strength for 5 combats	Tea Master (150 Gold)
Forgotten Soul	1 damage to a random enemy whenever you Exhaust	Grave of the Forgotten
Fragrant Mushroom	Lose 15 HP, Upgrade 2 random cards	Hungry for Mushrooms
Fresnel Lens	Block cards you add get Nimble 2	Drowning Beacon
Hand Drill	2 Vulnerable when you break an enemy's Block	Trash Heap
History Course	At the start of your turn, play a copy of your last played Attack or Skill; Attacks only on the public beta since v0.109.0	War Historian, Repy
Lost Wisp	8 damage to ALL enemies per Power played	The Lost Wisp
Maw Bank	12 Gold per floor until you spend Gold at a shop	Trash Heap
Mr. Struggles	Damage equal to the turn number to ALL enemies each turn	Doll Room
Pollinous Core	Every 4 turns, draw 2 additional cards	Colossal Flower
Royal Poison	Lose 4 HP at the start of each combat	The Round Tea Party
Sword of Jade	3 Strength each combat	Not stated by a source
Sword of Stone	Transforms into a powerful Relic after defeating 5 Elites	The Sunken Statue
Tea of Discourtesy	2 Dazed next combat	Tea Master (free)
The Boot	Unblocked attack damage of 4 or less becomes 5, Osty's attacks included	Trash Heap
The Chosen Cheese	+1 Max HP after each combat	Room Full of Cheese
Wongo Customer Appreciation Badge	"Does nothing"	Not stated by a source
Wongo's Mystery Ticket	3 random Relics after 5 combats	Welcome to Wongo's

Source: OP.GG relic list and OP.GG event pages (game data, beta v0.111.0), read Oct 26, 2026; History Course from Mega Crit's v0.109.0 notes (Jul 17, 2026) and PCGamesN (Mar 9, 2026); The Boot from v0.107.0; Byrd Swoop from PCGamesN.

Byrd Swoop, the card that comes from hatching the Byrdonis Egg, is a 0-cost Colorless Attack that deals 14 damage, per PCGamesN (Mar 9, 2026). OP.GG also lists a "Circlet" ("It's a circlet.") with no rarity and no pool; what it is for is not known.

Ancient relics

5:05 Ancient relics are given only by the eight Ancients, one at the start of each act: Neow and the Ancients covers each Ancient. They replace the boss relics of Slay the Spire (2019): Mega Crit (Nov 13, 2025) says Neow greets you at the start of the run and Acts 2 and 3 have "their own separate pools of random Ancients". Each Ancient offers three blessings, from three separate pools, and you take one; in co-op every player chooses their own.

Neow (Act 1)

Relic	Effect
Arcane Scroll	Upon pickup, obtain a random Rare Card to add to your Deck
Booming Conch	At the start of Elite combats, draw 2 additional cards and gain 1 Energy
Cursed Pearl	Upon pickup, receive Greed (an Eternal, Unplayable curse) and gain 333 Gold
Dowsing Rod	Public beta only (v0.109.0): add 1 Dowsing, a Quest card that becomes Abundance after 5 more ? rooms
Fishing Rod	Every 3 normal combats, Upgrade a random card in your Deck
Golden Pearl	Upon pickup, gain 150 Gold
Hefty Tablet	Choose 1 of 3 Rare cards to add to your Deck, and add 1 Injury to your Deck
Kaleidoscope	Upon pickup, obtain 2 card rewards from other characters
Large Capsule	Obtain 2 random Relics; add an additional Strike and Defend to your Deck
Lava Rock	The Act 1 Boss drops 2 Relics
Lead Paperweight	Choose 1 of 2 Colorless cards to add to your Deck
Leafy Poultice	Transform 1 of your Strikes and 1 of your Defends and lose 12 Max HP
Lost Coffer	Gain 1 card reward and procure 1 random potion
Massive Scroll	Multiplayer only: choose 1 of 3 Multiplayer Cards to add to your Deck
Neow's Bones	Gain 2 random Neow Relics and add 1 random Curse to your Deck
Neow's Sacrifice	Public beta only (v0.109.0): procure 1 Ambergris and add 1 Guilty to your Deck
Neow's Talisman	Upgrade 1 of your Strikes and 1 of your Defends
Neow's Torment	Add 1 Neow's Fury to your Deck
New Leaf	Transform 1 card
Nutritious Oyster	Raise your Max HP by 11
Phial Holster	Gain 1 potion slot and procure 2 random Potions
Pomander	Upgrade a card
Precarious Shears	Remove 2 cards from your Deck and lose 16 HP
Precise Scissors	Remove 1 card from your Deck
Scroll Boxes	Choose 1 of 2 packs of cards to add to your Deck
Silken Tress	Lose all Gold; Enchant all cards in your first card reward with Glam
Silver Crucible	The first 3 card rewards you see are Upgraded; the first Treasure Chest you open is empty
Small Capsule	Obtain a random Relic
Stone Humidifier	Whenever you Rest at a Rest Site, raise your Max HP by 5
Winged Boots	You may ignore paths when choosing the next rooms to travel to 3 times

Source: OP.GG: Neow (v0.111.0), read Oct 26, 2026; Dowsing Rod and Neow's Sacrifice from Mega Crit's v0.109.0 notes (Jul 17, 2026).

Act 2 Ancients: Orobas, Pael, Tezcatara

Ancient	Relic	Effect
Orobas	Alchemical Coffer	Gain 4 potion slots filled with random Potions
Orobas	Archaic Tooth	Transform a starter card into an ancient version
Orobas	Driftwood	You may reroll each card reward once
Orobas	Electric Shrymp	Enchant a Skill with Imbued
Orobas	Glass Eye	Obtain 2 Common cards, 2 Uncommon cards, and 1 Rare card
Orobas	Prismatic Gem	Gain 1 Energy at the start of each turn; card rewards contain cards from other colors
Orobas	Radiant Pearl	At the start of each combat, add 1 Luminesce into your Hand
Orobas	Sand Castle	Upgrade 6 random cards
Orobas	Sea Glass	See 15 cards from another character; choose any number to add to your Deck
Orobas	Touch of Orobas	Replace your starter Relic with an Ancient version
Pael	Pael's Blood	At the start of your turn, draw 1 additional card
Pael	Pael's Claw	Enchant all Defends with Goopy
Pael	Pael's Eye	The first time each combat you end your turn without playing cards, Exhaust your Hand and take an extra turn
Pael	Pael's Flesh	Gain an additional 1 Energy at the start of your 3rd turn and every turn after that
Pael	Pael's Growth	Enchant a card with Clone
Pael	Pael's Horn	Add 2 Relax to your Deck
Pael	Pael's Legion	Doubles Block gained from a card, then goes to sleep for 2 turns
Pael	Pael's Tears	If you end your turn with unspent Energy, gain an additional 2 Energy next turn
Pael	Pael's Tooth	Remove 5 cards from your Deck; after each combat, randomly add 1 back Upgraded
Pael	Pael's Wing	You may sacrifice card rewards to Pael; every 2 sacrifices, obtain a Relic
Tezcatara	Biiig Hug	Remove 4 cards from your Deck; whenever you shuffle your Draw Pile, add a Soot into it
Tezcatara	Golden Compass	Replace the Act 2 Map with a single special path
Tezcatara	Nutritious Soup	Enchant all Strikes with Tezcatara's Ember
Tezcatara	Pumpkin Candle	Gain 1 Energy at the start of each turn; extinguishes after 5 combats; Kindle it at Rest Sites
Tezcatara	Seal of Gold	At the start of your turn, spend 5 Gold to gain 1 Energy; 3 Gold on the public beta since v0.110.0
Tezcatara	Storybook	Add 1 Brightest Flame to your Deck
Tezcatara	Toasty Mittens	Main branch: at the start of your turn, Exhaust the top card of your Draw Pile and gain 1 Strength; on the public beta since v0.110.0 it Exhausts a card from your Hand
Tezcatara	Toy Box	Obtain 4 Wax Relics (5 on the public beta since v0.109.0); every 3 combats your left-most Wax Relic melts away
Tezcatara	Very Hot Cocoa	Start each combat with an additional 4 Energy
Tezcatara	Yummy Cookie	Upgrade 4 cards

Source: OP.GG event pages for Orobas, Pael and Tezcatara (v0.111.0), read Oct 26, 2026; Mobalytics: How Ancients Work (Jun 2, 2026) for Pael's Claw and Pael's Growth; beta changes from Mega Crit's v0.109.0 and v0.110.0 notes.

Act 3 Ancients: Nonupeipe, Tanx, Vakuu

Ancient	Relic	Effect
Nonupeipe	Beautiful Bracelet	Main branch: Enchant 3 cards with Swift 3; public beta (v0.111.0): 4 random cards with Swift 2
Nonupeipe	Blessed Antler	Gain 1 Energy at the start of each turn; shuffle 3 Dazed into your Draw Pile each combat
Nonupeipe	Brilliant Scarf	The 5th card you play from your hand each turn is free
Nonupeipe	Delicate Frond	At the start of each combat, fill all empty potion slots with random Potions
Nonupeipe	Diamond Diadem	Main branch: whenever you play 2 or fewer cards in a turn, take half damage from enemies; public beta (v0.109.0): start combat with 20 Block that is not removed at the start of your 2nd turn
Nonupeipe	Fur Coat	Mark 7 random combats (8 on the public beta since v0.110.0); enemies in those rooms have 1 HP
Nonupeipe	Glitter	Enchant all card rewards with Glam
Nonupeipe	Jewelry Box	Add 1 Apotheosis to your Deck
Nonupeipe	Looming Fruit	Raise your Max HP by 31
Nonupeipe	Signet Ring	Gain 999 Gold (888 on the public beta since v0.110.0)
Tanx	Claws	Transform up to 6 cards into Maul
Tanx	Crossbow	At the start of your turn, add a random Attack into your Hand; it is free to play this turn
Tanx	Iron Club	Every 4 cards you play, draw 1 card
Tanx	Meat Cleaver	You may Cook at Rest Sites
Tanx	Sai	At the start of your turn, gain 7 Block
Tanx	Spiked Gauntlets	Gain 1 Energy at the start of each turn; Powers cost 1 more Energy
Tanx	Tanx's Whistle	Add 1 Whistle to your Deck
Tanx	Throwing Axe	The first card you play each combat is played an extra time
Tanx	Tri-Boomerang	Choose 3 Attacks in your Deck and Enchant them with Instinct
Tanx	War Hammer	Whenever you kill an Elite, Upgrade 4 random cards
Vakuu	Blood-Soaked Rose	Add 1 Enthralled to your Deck; gain 1 Energy at the start of each turn
Vakuu	Choices Paradox	At the start of each combat, add 1 of 5 random cards into your Hand and give it Retain
Vakuu	Distinguished Cape	Main branch: lose 9 Max HP, add 3 Apparitions; public beta (v0.109.0): add 2 random Curses and 3 Apparitions
Vakuu	Fiddle	At the start of each turn, draw 2 additional cards; you may not draw cards during your turn
Vakuu	Jeweled Mask	At the start of each combat, put a random Power from your Draw Pile into your Hand; it is free this combat
Vakuu	Lord's Parasol	When you encounter the Merchant, immediately obtain EVERYTHING he sells
Vakuu	Music Box	Create an Ethereal copy of the first Attack you play each turn
Vakuu	Preserved Fog	Remove 3 cards from your Deck and add Folly to your Deck
Vakuu	Sere Talon	Main branch: add 2 random Curses and 3 Wishes; public beta (v0.109.0): lose 9 Max HP and add 3 Wishes
Vakuu	Whispering Earring	Gain 1 Energy at the start of each turn; Vakuu plays your first turn for you

Source: OP.GG event pages for Nonupeipe, Tanx and Vakuu (v0.111.0), read Oct 26, 2026; beta changes from Mega Crit's v0.109.0, v0.110.0 and v0.111.0 notes.

Darv (Act 2 or Act 3)

Relic	Effect
Astrolabe	Transform 3 cards, then Upgrade them
Black Star	Elites drop an additional Relic when defeated
Calling Bell	Obtain a unique Curse and 3 Relics
Dusty Tome	Obtain an Ancient Card (character specific)
Ectoplasm	You can no longer gain Gold; gain 1 Energy at the start of each turn
Empty Cage	Remove 2 cards from your Deck
Pandora's Box	Transform ALL Strikes and Defends
Philosopher's Stone	Gain 1 Energy at the start of each turn; ALL enemies start combat with 1 Strength
Runic Pyramid	At the end of your turn, you no longer discard your Hand
Snecko Eye	At the start of your turn, draw 2 additional cards; start each combat Confused
Sozu	Gain 1 Energy at the start of each turn; you can no longer obtain Potions
Velvet Choker	Gain 1 Energy at the start of each turn; you cannot play more than 6 cards per turn

Source: OP.GG: Darv (v0.111.0), read Oct 26, 2026.

Wax relics and the Fake Merchant's copies

Two groups of relics exist only in special cases. Wax Relics are temporary copies from Tezcatara's Toy Box that melt away one at a time every 3 combats, per OP.GG. The Fake Merchant ("The Merchant???") sells weaker copies marked "???", which you keep by beating him: Anchor??? (4 Block), Blood Vial??? (heal 1 HP), Happy Flower??? (Energy every 5 turns), Lee's Waffle??? (heal 10% of HP), Mango??? (+3 Max HP), Orichalcum??? (3 Block), Snecko Eye??? (start Confused), Strike Dummy??? (+1 damage), Venerable Tea Set??? (+1 Energy) and The Merchant's Rug??? ("Poor imitation. Does nothing."), per OP.GG's relic list.

New relic mechanics

Slay the Spire 2 relics do things the first game's could not, mostly through its new systems. Several shop and event relics Enchant cards (Gnarled Hammer, Kifuda, Punch Dagger, Royal Stamp, Wing Charm, Fresnel Lens; see Enchantments and Afflictions), Byrdpip gives you a pet that fights beside you, and Neow's Dowsing Rod and Neow's Torment put special cards in your deck. Ancients replace boss relics, so energy relics now come with a cost: PC Gamer's Harvey Randall wrote (May 15, 2026) that in the first game beating an act "nearly always" meant taking an energy relic, while in the sequel energy relics often carry major downsides.

Patch changes

Mega Crit has retuned relics in most patches. The changes that reached the main branch with Major Update #1 (v0.103.2, Apr 17, 2026) or Major Update #2 (v0.107.1, Jun 19, 2026):

Relic	Change	Patch
Amethyst Aubergine	10 to 15 Gold per enemy	v0.100.0
Book of Five Rings	Heal 15 to 20 HP	v0.100.0
Bowler Hat	20% to 25% Gold; gold relics leave the Merchant	v0.100.0
Planisphere	Heal 4 to 5 HP	v0.100.0
Permafrost	6 to 7 Block; Common to Uncommon (v0.101.0)	v0.100.0
Stone Cracker	Was boss fights only with 3 cards; now every combat, 2 cards	v0.100.0
All shop relics	25 Gold cheaper	v0.100.0
Pendulum	Reworked from "Whenever you shuffle your Draw Pile, draw a card"	v0.101.0
Bag of Marbles, Red Mask	Uncommon to Common	v0.101.0
Lasting Candy	Rare to Uncommon	v0.101.0
Bellows	Uncommon to Rare	v0.101.0
Tiny Mailbox	Common to Uncommon; 1 to 2 potions	v0.101.0
Regalite	Any created card gives Block, not only Colorless ones	v0.103.0
Infused Core	Lightning deals 1 additional damage	v0.105.0
Mummified Hand	Prefers cards that cost 1 or more	v0.106.0
The Boot	Also applies to Osty's attacks	v0.107.0
Gnarled Hammer	Can no longer be traded at the Relic Trader	v0.107.0

Sources: Mega Crit's patch notes v0.100.0, v0.101.0, v0.103.0, v0.105.0, v0.106.0 and v0.107.0.

On the public beta (v0.108.0 to v0.111.0, Jul 3 to Aug 14, 2026), Mega Crit changed Divine Destiny, Regalite, History Course, Diamond Diadem, Seal of Gold, Toy Box, Signet Ring, Fur Coat, Beautiful Bracelet, Toasty Mittens, Distinguished Cape, Sere Talon and others, as the tables note. Those changes are not on the main branch.

Best relics

9:12 Which relics are best depends on the character and the deck, and the published lists are opinions. Mobalytics' relic tier list, curated by the player JapaneseExport and updated Jul 27, 2026, leaves out Ancient and starter relics and puts in S tier Pocketwatch, Gambling Chip, Data Disk, Fresnel Lens, History Course, Pollinous Core, Razor Tooth, Bag of Preparation, Horn Cleat, Funerary Mask, Anchor, Gorget, Lizard Tail, Captain's Wheel, Runic Capacitor, Toxic Egg, Mummified Hand, Sturdy Clamp, Meat on the Bone, Cloak Clasp, Self-Forming Clay, Book Repair Knife, Regalite, Gold-Plated Cables, Potion Belt, Paper Krane, Emotion Chip, Red Skull, Centennial Puzzle, Mini Regent, Kifuda, Oddly Smooth Stone, Tuning Fork, Lunar Pastry and Galactic Dust. Its D tier includes Juzu Bracelet, Lava Lamp, Bone Tea, Belt Buckle, Dingy Rug, Bing Bong, Brimstone, Big Mushroom and Screaming Flagon.

1:50:04 PC Gamer's editors single out the shop's Miniature Tent. In their Sep 18, 2026 panel they call it "the absolute turbo nuts in Act 1", and Harvey Randall calls it an instant buy at high Ascension because it lets you Rest and Smith at once and stacks with Rest Site relics such as Shovel and Girya.

Untapped.gg's Dillon Skiffington (Apr 2026) reads relics as signals for a build, such as Red Skull, Vajra and Self-Forming Clay for a self-damage Ironclad or Kunai and Shuriken for a Shiv Silent, and names traps: Velvet Choker kills decks that play many cards a turn, Brimstone only pays off in short fights, and Ectoplasm means skipping Gold events and shops. He warns: "Forcing a build around a single Relic when your cards point somewhere else is how you die in Act 2".

Frequently asked questions

How many relics are in Slay the Spire 2? OP.GG counts 298 relics in Slay the Spire 2's v0.111.0 public-beta game data, across Starter, Common, Uncommon, Rare, Shop, Event and Ancient. Destructoid counted "over 250" at launch.

What are the starter relics in Slay the Spire 2? Slay the Spire 2's starter relics are Burning Blood (Ironclad), Ring of the Snake (Silent), Divine Right (Regent), Bound Phylactery (Necrobinder) and Cracked Core (Defect), per OP.GG. Orobas' Touch of Orobas upgrades each to an Ancient version, such as Black Blood or Divine Destiny.

What are the best relics in Slay the Spire 2? No single list decides it: Mobalytics' Jul 27, 2026 tier list puts Pocketwatch, Gambling Chip, Razor Tooth, Lizard Tail and over 30 others in S tier for Slay the Spire 2. PC Gamer's editors call the shop's Miniature Tent an instant buy at high Ascension.

What relics does the shop sell in Slay the Spire 2? The Merchant in Slay the Spire 2 sells normal relics and Shop relics, such as Miniature Tent, Membership Card, Mystic Lighter, Cauldron and Orrery, per OP.GG. Since v0.100.0 they cost 25 Gold less and Gold-generating relics are not sold.

Are there boss relics in Slay the Spire 2? No: Slay the Spire 2 replaces boss relics with Ancient relics, offered by Ancients such as Orobas and Tanx at the start of Acts 2 and 3, per Mega Crit. Neow offers Ancient relics at the start of the run.

What does Touch of Orobas do in Slay the Spire 2? Touch of Orobas, a blessing from Slay the Spire 2's Act 2 Ancient Orobas, replaces your starter relic with an Ancient version, per OP.GG: for example Burning Blood becomes Black Blood, which heals 12 HP after each combat instead of 6.

What does the Sword of Stone do in Slay the Spire 2? The Sword of Stone, from Slay the Spire 2's Sunken Statue event, "transforms into a powerful Relic after defeating 5 Elites", per OP.GG. Untapped.gg notes it rewards Elite-heavy paths.

Sources

Slay the Spire 2 Relics, Complete Relic List, OP.GG (game data v0.111.0), read Oct 26, 2026
Neow, Orobas, Pael, Tezcatara, Nonupeipe, Tanx, Vakuu, Darv, OP.GG event pages (v0.111.0), read Oct 26, 2026
The Neowsletter - November 2025, Mega Crit, Nov 13, 2025
Beta Patch Notes - v0.100.0, Mega Crit, Mar 20, 2026
Beta Patch Notes - v0.101.0, Mega Crit (Anthony Giovannetti), Mar 27, 2026
Beta Patch Notes - v0.103.0, Mega Crit, Apr 10, 2026
Major Update #1 - v0.103.2, Mega Crit, Apr 17, 2026
Beta Patch Notes - v0.105.0, Mega Crit, May 8, 2026
Beta Patch Notes - v0.106.0, Mega Crit, May 22, 2026
Beta Patch Notes - v0.107.0, Mega Crit, Jun 4, 2026
Major Update #2 - v0.107.1, Mega Crit, Jun 19, 2026
Beta Patch Notes - v0.108.0, Mega Crit, Jul 3, 2026
Beta Patch Notes - v0.109.0, Mega Crit, Jul 17, 2026
Beta Patch Notes - v0.110.0, Mega Crit, Jul 31, 2026
Beta Patch Notes - v0.111.0, Mega Crit, Aug 14, 2026
All relics in Slay the Spire 2 and their effects, Destructoid (Arka Sarkar), Mar 8, 2026
How to unlock all Epochs in Slay the Spire 2, Destructoid (Arka Sarkar), Mar 7, 2026
Slay The Spire 2: Tips And Tricks For Getting Started, Kotaku (Lewis Parker), Mar 18, 2026
What does the Lantern Key do in Slay the Spire 2?, PCGamesN (Paul Kelly), Mar 9, 2026
What does the Byrdonis Egg do in Slay the Spire 2?, PCGamesN (Paul Kelly), Mar 9, 2026
How Ancients Work, Mobalytics, Jun 2, 2026
Slay the Spire 2 Relic Tier List, Mobalytics (JapaneseExport), Jul 27, 2026
After close to 140 hours with it, I think Slay the Spire 2 feels more like a sequel than a DLC, PC Gamer (Harvey Randall), May 15, 2026
After 894 hours in Slay the Spire 2, these are our 12 strongest opinions, PC Gamer (Evan Lahti, Harvey Randall, Austin Wood), Sep 18, 2026
The Best Relics in Slay the Spire 2: Identifying Directional Relic Signals, Untapped.gg (Dillon Skiffington), Apr 2026
Which Relics Are Worth Your Gold? | Slay the Spire 2 Ascension 10 Guide, vmService, May 19, 2026 (video)
Ranking every Ancient boon in Spire 2 | Thoughts from a top STS player, JapaneseExport, Mar 21, 2026 (video)
The Optimal Choice for EVERY Event in Slay the Spire 2, vmService, Aug 25, 2026 (video)
Slay the Spire 2 - 15 Biggest Changes From Slay the Spire 1, IGN, Mar 7, 2026 (video)
Slay the Spire 2: Q&A with Anthony & Dani of Mega Crit, Manifest Conference, Jul 10, 2026 (video)

Moments

Which Relics Are Worth Your Gold? | Slay the Spire 2 Ascension 10 Guide

vmService

0:17 Slay the Spire 2 has relics in seven rarities, Starter, Common, Uncommon, Rare, Shop, Event and Ancient, and OP.GG's…
1:50:04 PC Gamer's editors single out the shop's Miniature Tent. In their Sep 18, 2026 panel they call it "the absolute turbo…

Ranking every Ancient boon in Spire 2 | Thoughts from a top STS player

JapaneseExport

39:40 Every character starts with one relic, and the Act 2 Ancient Orobas can upgrade it: his blessing Touch of Orobas…

The Optimal Choice for EVERY Event in Slay the Spire 2